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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not available
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Pharmacology and Toxicology of the Rare Earth Elements
Author:
Haley, T. J
Year:
1965
Bibliographic source:
Journal of Pharmaceutical.Sciences 54.5 (1965): 663-70

Materials and methods

GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
Lanthanum oxide
EC Number:
215-200-5
EC Name:
Lanthanum oxide
Cas Number:
1312-81-8
Molecular formula:
La2O3
IUPAC Name:
lanthanum(3+);oxygen(2-)

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 10 000 mg/kg bw

Applicant's summary and conclusion