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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The long-term toxicity of Chlorhexidine gluconate 20 % Solution was evaluated in a 28 day juvenile fish growth test (Oncorhynchus mykiss) according to OECD TG 215 under semi-static test conditions.The test item Chlorhexidine gluconate 20 % Solution caused significant reductions on weight gain of 20.5, 24.7 and 27.4% at test concentrations of 0.36, 1.02 and 2.86 mg test item/L nominal (equivalent to 0.11, 0.20, 1.02 mg test item/L mean measured) considering 28 days after exposure start. The corresponding NOEC was 0.13 mg test item/L nominal (0.065 mg test item/L mean measured).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Dose descriptor:
NOEC
Effect concentration:
0.012 mg/L

Additional information